A lot of it is psychology. It's one team playing with some added pressure of losing to a inferior opponent vs a team that has nothing to lose and plays loosey goosey.
If you watch MLB in September you'll see plenty of occasions a team in the pennant race loses to a team at the bottom of the standings by record. One team playing with loads of pressure where mistakes are magnified and the other team is playing with nothing to lose.
An interesting question I ask myself is what would the Xavier program have looked like now and over the last couple decades if they never would have had UC on their schedule?
How would UC fair without X on their schedule?